Ph.D. position in solution-state NMR in Nantes, France

A Ph.D. position is available in the NMR team of the CEISAM laboratory in The Ph.D. student will join an ANR-funded project, and be supervised by Jean- Nicolas Dumez and Aurélie Bernard at CEISAM, and Nicolas Blanchard from the LIMA lab. The project aims at developing methods for the online/in-line monitoring of chemical reactions by flow NMR, and applying these methods to investigate organic chemical reactions. The project will build on the team’s experience with the development of flow NMR method for the analysis of mixtures. The Ph.D. student will in particular: . Develop NMR methods that yield all or parts of the spectrum of compounds of interest, directly from a reaction mixture . Integrate these methods in setups for online monitoring by flow NMR, . Apply these methods, through collaborations, to the flow monitoring of chemical reactions in batch and flow Applicants should have a background in chemistry (preferentially analytical or physical) or physics, and a strong interest in both fundamental and applied aspects of magnetic resonance. The NMR team of the CEISAM lab works on method developments in solution-state NMR and their application to the analysis of mixtures. It is equipped with state-of-the-art NMR spectrometers, in the 400 to 700 MHz range, a flow NMR system and a polariser for dissolution-DNP. CEISAM is the molecular chemistry lab of the Université de Nantes, where research includes physical and analytical chemistry, organic synthesis and catalysis, and chemical biology. The lab is located in the vibrant city of Nantes, close to the Atlantic Coast of south Brittany. The position is for 3 years Please send applications including CV cover letter and the name of two J.-N. Dumez, NMR methods for the analysis of mixtures, Chem. Commun. 53, 13855 (2022). DOI : 10.1039/D2CC05053F Felpin, and J.-N. Dumez, In-line Multidimensional NMR Monitoring of Photochemical Flow Reactions, Chem. Eur. J., e202203240 (2023). DOI : 10.1002/ chem.202203240 C. Lhoste, M. Bazzoni, J. Bonnet, A. Bernard, F.-X. Felpin, P. Giraudeau, and J.-N. Dumez, Broadband ultrafast 2D NMR spectroscopy for online monitoring in M. Bazzoni, R. Mishra, and J.-N. Dumez, Single-Scan Ultraselective NMR Experiments with Preserved Sensitivity, Angew. Chem. Intl. Ed. e202314598 #J-18808-Ljbffr