Microscopy Engineer/Microscopist (M/F)

Organization: UMR703 PAnTher INRAE/ONIRISDescription of the missionThe engineer will support APEX by maintaining different state of the art wide-field, confocal,multispectral, multiphoton and super-resolution (STORM/PALM/AiryScan/TIRF) microscopes; will contribute to user training at microscopes and image analysis; and will participate in the R&D activities in issue phenotyping and cell tracking.. Further information regarding the platform including the detailed list of equipment can be found at https://www6.inrae.fr/anatomie_pathologique_sante_animale .Working Environnement and scientific contextAPEX (Anatomical Pathology Expertise for research) is a platform dedicated to veterinary pathology and fluorescence bio-imaging and focused on animal model characterization. Located at the Veterinary School of Nantes (Oniris) and set up in 2006 by the joint research unit 703 PAnTher, member of NeurATRIS, APEX carried out by the National Institute of Agronomic Research (INRA) and by Oniris is labelled IBiSA and BioGenouest, and certified ISO 9001.APEX is focused on the investigation of healthy and diseased animal tissues. To address scientific challenges, APEX is structured around experts with complementary skills offers integrated veterinary histopathology andfluorescence bio-imaging to scientific community, private or academic. Thanks to an original synergy between the knowledge of normal and pathologic animal tissue and skills in bio-imaging, APEX initiates newdevelopments with a constant concern to strengthen the technological and methodological offer in the field of tissue and cell phenotype (level of detection, tracking, quantification, specific multi-labelling, quantitativehistopathology).APEX originally proposes an integrated offer in animal tissue phenotype and synergizes the skills of veterinary pathologists, certified by the European board committee and of engineers R&D specialized in fluorescence bioimaging. APEX facility core can set-up pathology and bio-imaging services in:– all types of tissues and organs with an additional long-term recognized experience in neuropathology and muscle pathology;– a very large range of species (from animal models, with a solid track record in large ones, to livestock target species and wild sentinel species) as veterinary pathologists are specially trained to comparative pathology;– studies compliant with drug regulatory agencies (EMA, FDA…);– studies requiring leading-edge bio-imaging technology (biphotonic, super-resolution microscopy PALM/STORM, spectral imaging, slide scanner…).Major tasksChoose and customize imaging systems to deal with scientifics purposesDevelop new methodologies in bio-imaging and sample preparationAnalyse and interprete microscopic images and clearly present results.Train and ensure technology transfer to platform usersAdvise and train users for sample preparation and analytical methodsDevelop solutions for image analysesWrite technical notes and tutorialsScientific and technical monitoring in fluorescence bio-imagingDesign and implement trainingsSkillsKnowledge and experience in confocal microscopy, high resolution, multiphoton.Skills in optic will be appreciatedKnow how to use informatic tools and softwares dedicated to image acquisition and image analyses (FIJI, NIS, Huygens, Amira)Skills in informatic will be appreciatedPlan activities of the platform in accordance with external constraints and deadlinesCommunicate and manage relationships with collaboratorsPersonal capacitiesEnthusiastic person with a technical or research backgroundUniversity degree in life sciences or physics (master, Engineer or PhD)Practical experience in at least two or more of the following fields: Optics, light microscopy techniques (widefield and/or confocal), image processing.Rigorous, reliable, well organizedAutonomy in the management of the requested missionsIntitiatives and organization skillsEducation abilities, sense of contact, courtesyRequired degreeUniversity degree in life sciences or physics (master, Engineer or PhD)LangageFrench language skillsSkills in English greatly appreciated #J-18808-Ljbffr